Ka hopena bactericidal o ka hyperbaric oxygen therapy i nā ʻeha kuni

Hoʻolauna

Loaʻa pinepine nā ʻeha kuni i nā hihia pilikia a lilo pinepine ia i puka komo no nā pathogens. ʻOi aku ma mua o 450,000 mau ʻeha kuni e hana ʻia i kēlā me kēia makahiki e make ana ma kahi o 3,400 mau make ma ʻAmelika Hui Pū ʻIa. ʻO ka nui o ka ʻeha kuni ma Indonesia he 0.7% i ka makahiki 2013. ʻOi aku ma mua o ka hapalua o kēia mau mea Wahi a kekahi mau noiʻi e pili ana i ka hoʻohana ʻana i nā maʻi i mālama ʻia no nā maʻi bacteria, ʻo kekahi o ia mau mea i kūʻē i kekahi mau antibiotics. Ke hoʻohana neika lāʻau lapaʻau oxygen hyperbaric(HBOT) no ka mālama ʻana i nā kuni he nui nā hopena maikaʻi e pili ana i ka mālama ʻana i nā maʻi bacteria, a me ka hoʻolalelale ʻana i ke kaʻina hana ho'ōla ʻeha. No laila, ke manaʻo nei kēia haʻawina e hōʻoia i ka pono o HBOT i ka pale ʻana i ka ulu ʻana o ka bacteria.

Nā ʻAno Hana

He haʻawina noiʻi hoʻokolohua kēia i nā lāpaki e hoʻohana ana i kahi hoʻolālā hui kaohi ma hope o ka hoʻāʻo. Ua hāʻawi ʻia he 38 mau lāpaki i nā kuni ʻelua kekelē ma ka ʻāpana poʻohiwi me kahi papa hao metala i hoʻomehana mua ʻia no 3 min. Ua lawe ʻia nā moʻomeheu bacteria i nā lā 5 a me 10 ma hope o ka hōʻike ʻana i nā kuni. Ua māhele ʻia nā laʻana i ʻelua mau pūʻulu, HBOT a me ka kaohi. Ua hana ʻia nā loiloi helu me ka hoʻohana ʻana i ke ʻano Mann-Whitney U.

Nā Hualoaʻa

ʻO nā bacteria Gram-negative ka pathogen i loaʻa pinepine ʻia ma nā hui ʻelua. ʻO Citrobacter freundi ka bacteria Gram-negative maʻamau (34%) i loaʻa i nā hopena moʻomeheu o nā hui ʻelua.

I ka hoʻohālikelike ʻana me ka hui kaohi, ʻaʻohe ulu ʻana o ka bacteria i loaʻa i nā hopena moʻomeheu o ka hui HBOT, (0%) vs (58%). Ua ʻike ʻia kahi emi nui o ka ulu ʻana o ka bacteria ma ka hui HBOT (69%) i hoʻohālikelike ʻia me ka hui kaohi (5%). Ua kū mālie nā pae bacteria ma 6 mau lāpaki (31%) ma ka hui HBOT a me 7 mau lāpaki (37%) ma ka hui kaohi. Ma keʻano holoʻokoʻa, ua emi nui ka ulu ʻana o ka bacteria ma ka hui mālama HBOT i hoʻohālikelike ʻia me ka hui kaohi (p < 0.001).

Hopena

Hiki i ka hoʻokele HBOT ke hōʻemi nui i ka ulu ʻana o ka bacteria i nā ʻeha kuni.